Acquired Hemophilia A (AHA) related to pregnancy is a rare but life-threatening autoimmune disorder where the body develops antibodies against its own clotting Factor VIII. Unlike hereditary hemophilia, which is genetic, this form typically appears in women with no prior history of bleeding. It most commonly occurs in the , often 1 to 4 months after delivery. Key Features & Diagnosis
Recombinant activated Factor VII (rFVIIa) or activated prothrombin complex concentrates (FEIBA). Eradicating the Inhibitor Download HГ©mophilie acquise grossesse pdf
An isolated prolongation of the activated partial thromboplastin time (aPTT) that does not correct when mixed with normal plasma. Acquired Hemophilia A (AHA) related to pregnancy is
Used to stop active bleeding by circumventing the inhibited Factor VIII. Key Features & Diagnosis Recombinant activated Factor VII
Sudden, severe bruising (ecchymosis), mucosal bleeding, or prolonged bleeding after delivery.
High-dose corticosteroids (Prednisone) are the standard first step, sometimes combined with Cyclophosphamide or Rituximab.