Guanosine 5 - g-thio triphosphate = 75 HPLC, powder 94825-44-2
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across plasma membranes, simulating receptor-activated signaling (e.g., by vasopressin).
-S), a non-hydrolyzable analog of GTP. It is widely used in biochemical research as a .
Soluble in water, commonly used at high concentrations (e.g., ≥75is greater than or equal to 75 5. Regulatory and Safety Storage Class: 11 (Combustible Solids).
It is a standard reagent used to keep G-proteins in a perpetually active state during studies of kinase activity and GPCR (G-protein-coupled receptor) signaling.
-S) is a thiophosphate analog of guanosine triphosphate (GTP). The key difference is the substitution of a sulfur atom for an oxygen atom on the terminal phosphate group (γ-phosphate). G8634-1MG CAS Number: 94825-44-2 Formula: Molecular Weight: 562.98 Appearance: White to off-white powder Assay: 2. Biological Mechanism of Action The primary utility of GTP- -S lies in its resistance to hydrolysis by GTPases.
Solutions are very unstable; they must be prepared immediately prior to use.