If there is hair, with scissors. Do not shave, as this can irritate the skin and increase absorption. Ensure the skin is completely dry. Apply the Patch :
: Most fentanyl patches are changed every 72 hours (3 days), though some patients may require changes every 48 hours if prescribed by a doctor. Application Instructions Pain Patch For Cancer Patients
: Always apply the new patch to a different skin site to prevent irritation and ensure consistent absorption. Transdermal Opioids for Cancer Pain Management - PMC If there is hair, with scissors