Pearlcam Access
Before a new cancer drug or imaging agent can be tested on humans, it must be proven effective and safe in animal models. Systems like the LI-COR Pearl Trilogy provide the high-quality data required by regulatory bodies (like the FDA) to move a discovery from the lab to the clinic.
The system is a staple in laboratories focusing on translational medicine. Key use cases include: 1. Fluorescence-Guided Surgery
Capabilities typically include 700 nm and 800 nm channels, allowing researchers to track two different biological markers simultaneously. 📈 Key Applications in Research PearlCAM
High-sensitivity detection of signals from within internal organs or deep-seated tumors.
In the rapidly evolving landscape of cancer research, the ability to visualize biological processes in real-time within living organisms is paramount. PearlCAM (and the associated Pearl imaging systems) serves as a bridge between laboratory benchwork and clinical application, providing researchers with a non-invasive look at tumor progression and drug delivery. 🔬 Core Technology Before a new cancer drug or imaging agent
The software quantifies the signal intensity, allowing researchers to say exactly how much of a drug reached the target compared to healthy tissue. 🌟 Why It Matters
Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow Key use cases include: 1
Researchers use PearlCAM to test new "smart" dyes that attach specifically to cancer cells. By viewing the animal through the Pearl system, surgeons can practice identifying tumor margins that would be invisible to the naked eye. Washington University has utilized this for foundations in translational imaging. 2. Drug Delivery Tracking