: Investigating the trigeminal circuits responsible for complex motor patterns like chewing and swallowing. Clinically, these findings apply to disorders like dysphagia, Parkinson’s disease, and schizophrenia.
: Utilizing advanced techniques like single-cell transcriptomics and in vivo imaging to identify novel molecular targets, including ion channels and metabolic regulators, for more precise therapies. Translational Strategies
The goal of this research is to turn laboratory discoveries into better patient care through: Translating Mechanisms of Orofacial Neurological Disorder
The field focuses on several critical neurological and physiological mechanisms:
: A growing focus on how non-neuronal cells—such as satellite glial cells and macrophages in the trigeminal ganglion—regulate neuronal excitability and contribute to neuropathic pain.
: Research into the transition from acute to chronic pain, driven by peripheral and central sensitization . This includes studying "maladaptive plasticity" within the trigeminal system, where persistent signals lead to chronic conditions like temporomandibular disorders (TMD) .
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